Anticonvulsant and Anti-anxiety Effects of Royal Jelly in Adult Male Syrian Rats

Objective Royal jelly is a honey bee secretion with beneficial effects on the nervous system. The present study aims to investigate of royal in reducing seizure and anxiety-like behaviors Syrian rats. Methods This an experimental study. In model, 25 male white rats were randomly divided into five groups: Control, 100 mg/kg, 200 400 phenobarbital. After 30 minutes, strychnine was injected induce animals. time onset, duration, mortality rate animals recorded. anxiety 35 50 diazepam. Anxiety-like examined by using elevated plus maze (EPM) test. Data analysis performed one-way ANOVA, P<0.05 statistically significant. Results at doses mg/kg delayed onset reduced duration compared control group (P<0.05). also after different Moreover, increased spent open arms EPM platform number entries Conclusion Administration can reduce strychnine-induced modulate